Self Quiz for the Mutation Tutorial

Study the material in this section and then write out the answers to these question.
Do not just click on the answers and write them out. This will not test your understanding of this tutorial.

1. Match the following:

_____The sequence of deoxyribonucleotide bases in the genes that make up a organism's DNA. (ans)
_____ An error during DNA replication that results in a change in the sequence of deoxyribonucleotide bases in the DNA. (ans)
_____ Alternate forms of a gene. (ans)
_____ Mutations caused by mutagens, substances that cause a high rate of mutation. (ans)
_____ The physical characteristics of an organism. (ans)

a. genotype
b. phenotype
c. allele
d. mutation
e. spontaneous mutation
f. induced mutation

2. Describe 2 different mechanisms of spontaneous mutation. (ans)

3. Match the following:

_____ This is usually seen with a single substitution mutation and results in one wrong codon and one wrong amino acid (ans)
_____ If the change in the deoxyribonucleotide base sequence results in transcription of a stop, the protein is terminated at that point in the message. (ans)
_____ This is sometimes seen with a single substitution mutation when the change in the DNA base sequence results in a new codon still coding for the same amino acid. (ans)
_____ This is seen when a number of DNA nucleotides not divisible by three is added or deleted and all of the codons and all of the amino acids after that addition or deletion are usually wrong. (ans)

a. sense mutation
b. nonsense mutation
c. frameshift mutation
d. missense mutation

4. Briefly describe 3 ways chemical mutagens work. (ans)

5. Compare ultraviolet radiation and gamma radiation in terms of how they induce mutation. (ans)

6. As a result of a substitution mutation, a DNA base triplet AGA is changed to AGG. State specifically what effect this would have on the resulting protein (see Fig. 9). (ans)

7. A third triplet in a bacterial gene is TTT. A substitution mutation changes it to ATT. State specifically what effect this would have on the resulting protein (see Fig. 9). (ans)

 


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Updated: July 5, 2001