Bacterial Pathogenesis
An Overview to Microbial Pathogenesis
Virulence Factors that Promote Colonization of a Host
The Ability to Use Motility or Other Means to Contact Host Cells and Disseminate Within a Host
The Ability to Adhere to Host Cells and Resist Physical Removal
The Ability to Invade Host Cells
The Abilty to Compete for Iron and Other Nutrients
An Overview of Phagocytosis, the Complement Pathways, and Antibacterial Peptides, Key Parts of Innate Immune Responses
The Ability to Evade Innate Immune Responses such as Phagocytic Engulfment and Antibacterial Peptides
The Ability to Evade Innate Immune Responses such as Phagocytic Destruction
The Ability to Evade Adaptive Immune Responses
Virulence Factors that Damage or Harm the Host
The Ability of PAMPs to Trigger the Production of Inflammatory Cytokines that Result in an Excessive Inflammatory Response
Overall Mechanism
Gram-Negative Bacterial PAMPs
Gram-Positive Bacterial PAMPs
Acid-Fast Bacterial PAMPs
The Ability to Produce Harmful Exotoxins
An Overview of Exotoxins
Type I Toxins (Superantigens)
Type II Toxins (Toxins that Damage Host Cell Membranes)
Type III Toxins (A-B toxins and other Toxin that Interfere with Host Cell Function)
The Ability to Induce Autoimmune Responses