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This Concept Map, created with IHMC CmapTools, has information related to: LAB 16 - SEROLOGY, PART 2 - INDIRECT SEROLOGIC TESTING, serology types direct serologic testing, antigen chemical nature large molecular weight proteins and polysaccharides, indirect serologic testing general procedure A sample of the patient's serum is mixed with the known antigen for that suspected disease., indirect serologic testing examples The RPR test for syphilis, indirect serologic testing examples The western blot test for HIV infection, qualitative test description Only detects the presence or absence of specific antibodies in the patient's serum and is often used for screening purposes., indirect serologic testing description Used to detect antibodies being made against a specific antigen in the patient's serum. Antibodies in a person's serum being made by that individual against an antigen associated with a particular disease are detected using a known antigen., immunogen definition An antigen that is recognized by the body as nonself and stimulates an adaptive immune response., epitope definition The actual portions of an antigen that react with receptors on B-lymphocytes and T-lymphocytes, as well as with free antibody molecules; 5-15 amino acids, 3-4 sugar residues., direct serologic testing description Used to identify unknown antigens (such as microorganisms). A preparation known antibodies, called antiserum, is used to identify an unknown antigen., serology definitions humoral immunity, large molecular weight proteins and polysaccharides examples microbial structures, microbial exotoxins, allergens, foreign tissues and cells, the body's own cells that the body fails to recognize as "normal self", indirect serologic testing examples Serologic test for infectious mononucleosis, antigen chemical nature immunogen, The RPR test for syphilis description A presumptive serologic screening test for syphilis. Detects a non-specific anti-lipid antibody (traditionally termed reagin), which is not found in normal serum but is found in the serum of people with syphilis and several other diseases. The patient's serum is mixed with several known lipids bound to charcoal particles. Agglutination is positive., Used to detect antibodies being made against a specific antigen in the patient's serum. Antibodies in a person's serum being made by that individual against an antigen associated with a particular disease are detected using a known antigen. types quantitative test, humoral immunity definition The production of antibody molecules in response to an antigen; mediated by B-lymphocytes., serology definitions immunogen, The FTA-ABS test for syphilis description A confirming test for syphilis. Detects antibodies made against Treponema pallidum.The patient's serum is mixed with known T. pallidum on a microscope slide. If the test is positive, the spirochetes will fluoresce when viewed with a fluorescent microscope., quantitative test description A quantitative test gives the titer of that antibody in the serum.
