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This Concept Map, created with IHMC CmapTools, has information related to: Answers_phago_comp, the complement pathways benefits of proteins from the complement pathways inflammation, the complement pathways benefits of proteins from the complement pathways phagocyte chemotaxis, 1. attachment of microbe to phagocyte unenhanced attachment pathogen-associated molecular patterns or PAMPs on the microbe bind to endocytic pattern-recognition receptors on the surface of the phagocytes, 1. attachment of microbe to phagocyte enhanced attachment attachment of microbes to phagocytes by way of an antibody molecule called IgG or complement pathways proteins called C3b and C4b, Overview of Phagocytosis, Antibacterial Peptides, and the Complement Pathways antibacterial peptides Directly toxic by forming pores in the cytoplasmic membrane of a variety of microorganisms causing leakage of cellular needs., the complement pathways benefits of proteins from the complement pathways opsonization (enhanced attachment), 2. ingestion process Polymerization and then depolymerization of actin filaments send pseudopods out to engulf the microbe and place it in a vesicle called a phagosome., the complement pathways benefits of proteins from the complement pathways MAC lysis of biological membranes, inflammation role in body defense Body defense cells and defense chemicals leave the blood and enter the tissue around an injured or infected site., phagocytosis steps in phagocytosis 2. ingestion, 3. destruction intracellular destruction Lysosomes, containing digestive enzymes and microbicidal chemicals, fuse with the phagosome containing the ingested microbe and the microbe is destroyed., the complement pathways types classical complement pathway, the complement pathways types lectin pathway, phagocyte chemotaxis role in body defense enables the phagocytes to move toward the infected area in order to remove microorganisms, the complement pathways types alternative complement pathway, Polymerization and then depolymerization of actin filaments send pseudopods out to engulf the microbe and place it in a vesicle called a phagosome. then An electron pump brings protons (H+) into the phagosome. This lowers the pH within the phagosome so that when a lysosome fuses with the phagosome, the pH is correct for the acid hydrolases to effectively break down cellular proteins., Overview of Phagocytosis, Antibacterial Peptides, and the Complement Pathways overview of phagocytosis phagocytosis, phagocytosis steps in phagocytosis 1. attachment of microbe to phagocyte, phagocytosis steps in phagocytosis 3. destruction, Overview of Phagocytosis, Antibacterial Peptides, and the Complement Pathways overview of the complement pathways the complement pathways