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This Concept Map, created with IHMC CmapTools, has information related to: Answers_Antibiotic_Modeofaction_part1, Antibiotic/chemical agent inhibits normal nucleic acid replication. examples sulfonamides, trimethoprim, glycopeptides action bind to peptides of peptidoglycan monomers, polymyxin, chlorhexidine, alcohol, triclosans, orthophenylphenol, result causes leakage of cellular needs, Antibiotics and chemical agents affect bacterial structures or functions. mode of action Antibiotic or disinfectant alters cytoplasmic membrane., prevents synthesis of tetrahydrofolic acid leads to bacteria cannot synthesize the nucleotide bases thymine, guanine, uracil, and adenine, bacitracin action binds to bactoprenol, Antibiotic inhibits peptidoglycan synthesis. examples penicillins, cephalosporins, glycopeptides, bacitracin, interferes with the supercoiling, replication and separation of circular bacterial DNA result blocks the replication of bacterial DNA, Drig inhibit synthesis of acid-fast cell walls. examples INH, penicillins, cephalosporins, glycopeptides, bacitracin ???? bacitracin, penicillins, cephalosporins, glycopeptides, bacitracin ???? penicillins, cephalosporins, Drig inhibit synthesis of acid-fast cell walls. examples ethambutol, Bacteria are killed or their growth is inhibited. ???? Antibiotics and chemical agents affect bacterial structures or functions., bind to peptides of peptidoglycan monomers leads to no glycosidic or peptide bonds form; weak cell wall, no glycosidic or peptide bonds form; weak cell wall result osmotic lysis, metronidazole action puts nicks in the DNA strands of certain bacteria, puts nicks in the DNA strands of certain bacteria result blocks the replication of bacterial DNA, bacteria cannot synthesize the nucleotide bases thymine, guanine, uracil, and adenine result blocks the replication of bacterial DNA, fluoroquinolones action inhibits bacterial topoisomerase enzymes, penicillins, cephalosporins, glycopeptides, bacitracin ???? glycopeptides
