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This Concept Map, created with IHMC CmapTools, has information related to: Answers_Antiviral agents, HIV nucleoside-analog reverse transcriptase inhibitors action Chemically resemble a normal DNA nucleoside. Once inserted into the growing DNA chain it inhibits further proviral production, fomivirsen (Vitravene) mode of action A microRNA that has a nucleotide sequence complementary to a sequence in mRNA transcripts that encodes several proteins responsible for production of infectious CMV. Binding of fomivirsen to the target mRNA results in inhibition of viral protein synthesis., HIV nucleoside-analog reverse transcriptase inhibitors examples zidovudine (AZT; ZDV; Retrovir); didanosine (ddI; dideoxyinosine; Videx); stavudine (d4T; Zerit); lamivudine (3TC; Epivir); abacavir (ABC; Ziagen); emtricitabine (FTC; Emtriva, Coviracil), HIV mode of action HIV Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs), Antiviral Agents used to treat HIV, HIV mode of action HIV Protease Inhibitors (PIs), Integrase Inhibitors example raltegravir (Isentress), influenza viruses examples zanamivir (Relenza); oseltamivir (Tamiflu), hepatitis C virus (HCV) examples telaprevir (Incivek); boceprevir (Victrelis), amantadine (Symmetrel); rimantidine (Flumadine) mode of action blocks the uncoating step blocking viral replication, lamivudine (Epivir-HBV); adefovir dipivoxil (Hepsera) mode of action Chemically resemble a normal DNA nucleoside. Once inserted into the growing DNA chain it inhibits further viral DNA replication., Antiviral Agents used to treat herpes simplex viruses (HSV); varicella zoster virus (VZV), HIV Protease Inhibitors (PIs) examples saquinavir (SQV; Inverase); ritonavir (RTV; Norvir); idinavir (IDV; Crixivan); nelfinavir (NFV; Viracept); amprenavir (APV; Agenerase); atazanavir (ATV; Reyataz); fosamprenavir (FPV; Lexiva); ritonavir (RTV; Norvir) darunavir (DRV; TMC114; Prezista); tipranavir (TPV; Aptivus), HIV mode of action Integrase Inhibitors, Antiviral Agents used to treat influenza viruses, Antiviral Agents used to treat hepatitis C virus (HCV), telaprevir (Incivek); boceprevir (Victrelis) mode of action A protease inhibitor that binds to an HCV-encoded protease and prevents it from cleaving the long polyprotein from polycistronic HCV genes into proteins essential to the structure and function of HCV., acyclovir (Zovirax); famciclovir (Famvir); valacyclovir (Valtrex); penciclovir (Denavir); mode of action Chemically resemble a normal DNA nucleoside. Once inserted into the growing DNA chain it inhibits further viral DNA replication., cytomegaloviruses (CMV) examples gancyclovir (Cytovene; Vitrasert); valganciclovir (Valcyte); foscarnet (Foscavir); cidofovir (Vistide), influenza viruses examples amantadine (Symmetrel); rimantidine (Flumadine)