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This Concept Map, created with IHMC CmapTools, has information related to: Answers_intro_pathogenicity, Molecules expressed and secreted by that enable them to colonize the host, evade or inhibit the immune responses of the host, enter into or out of a host cell, and/or obtain nutrition from the host. role of quorum sensing Most of the virulence factors that enable bacteria to colonize the body and/or harm the body are the products of quorum sensing genes., In order for most bacteria to cause infectious disease or become normal flora of the body they must have the ability to colonize the body, that is, to establish themselves in or on the body and not be completely removed. colonization virulence factors The ability to compete for nutrients such as iron, Most of the virulence factors that enable bacteria to colonize the body and/or harm the body are the products of quorum sensing genes. virulence factors that permit colonization of the host In order for most bacteria to cause infectious disease or become normal flora of the body they must have the ability to colonize the body, that is, to establish themselves in or on the body and not be completely removed., In order for most bacteria to cause infectious disease or become normal flora of the body they must have the ability to colonize the body, that is, to establish themselves in or on the body and not be completely removed. colonization virulence factors The ability to invade host cells, In order for most bacteria to cause infectious disease or become normal flora of the body they must have the ability to colonize the body, that is, to establish themselves in or on the body and not be completely removed. colonization virulence factors The ability to resist Adaptive immunity, Most of the virulence factors that enable bacteria to colonize the body and/or harm the body are the products of quorum sensing genes. virulence factors that damage or injure the host The ability to induce autoimmune responses., Most of the virulence factors that enable bacteria to colonize the body and/or harm the body are the products of quorum sensing genes. virulence factors that damage or injure the host The ability to produce pathogen-associated molecular patterns (PAMPS) that bind to host cells causing them to synthesize and secrete inflammatory cytokines and chemokines., Infection versus Disease pathogenicity The ability of a microbe to cause disease and inflict damage upon its host., Most of the virulence factors that enable bacteria to colonize the body and/or harm the body are the products of quorum sensing genes. typically located in Pathogenicity islands or PAIs and are usually acquired by horizontal gene transfer involving conjugative plasmids., The degree of pathogenicity within a group or species of microbes. virulence factors Molecules expressed and secreted by that enable them to colonize the host, evade or inhibit the immune responses of the host, enter into or out of a host cell, and/or obtain nutrition from the host., Infection versus Disease To cause infectious disease a microorganism must: Adhere to cells of the skin or mucosa of its new host and colonize the body., In order for most bacteria to cause infectious disease or become normal flora of the body they must have the ability to colonize the body, that is, to establish themselves in or on the body and not be completely removed. colonization virulence factors The ability to resist innate immunity, Infection versus Disease infection When a microorganism has established itself in a host (has colonized that host) whether not it causing harm or impairing damage., In order for most bacteria to cause infectious disease or become normal flora of the body they must have the ability to colonize the body, that is, to establish themselves in or on the body and not be completely removed. colonization virulence factors The ability to adhere to host cells and resist physical removal, Infection versus Disease To cause infectious disease a microorganism must: Leave the reservoir via a portal of exit and gain access to the new host through a portal of entry., Autoinducers produced by one bacterium cross the membrane of another and bind to receptors in its cytoplasm. then Autoinducer/receptor complexes are able to bind to DNA promoters and activate the transcription of quorum sensing-controlled genes., Infection versus Disease To cause infectious disease a microorganism must: Maintain a reservoir before and after infection., Most of the virulence factors that enable bacteria to colonize the body and/or harm the body are the products of quorum sensing genes. quorum sensing The production, release, and community-wide sensing of molecules called autoinducers that modulate gene expression in response to the density of a bacterial population, Autoinducer/receptor complexes are able to bind to DNA promoters and activate the transcription of quorum sensing-controlled genes. benefit Individual bacteria within a group are able to benefit from the activity of the entire group., When a microorganism has established itself in a host (has colonized that host) whether not it causing harm or impairing damage. depends upon The virulence of the microorganism.