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This Concept Map, created with IHMC CmapTools, has information related to: Answers_phago_comp, phagocytosis steps in phagocytosis 3. destruction, 1. attachment of microbe to phagocyte unenhanced attachment pathogen-associated molecular patterns or PAMPs on the microbe bind to endocytic pattern-recognition receptors on the surface of the phagocytes, the complement pathways benefits of proteins from the complement pathways opsonization (enhanced attachment), the complement pathways benefits of proteins from the complement pathways MAC lysis of biological membranes, the complement pathways benefits of proteins from the complement pathways phagocyte chemotaxis, phagocytosis steps in phagocytosis 1. attachment of microbe to phagocyte, Overview of Phagocytosis and the Complement Pathways overview of the complement pathways the complement pathways, 3. destruction intracellular destruction Lysosomes, containing digestive enzymes and microbicidal chemicals, fuse with the phagosome containing the ingested microbe and the microbe is destroyed., Polymerization and then depolymerization of actin filaments send pseudopods out to engulf the microbe and place it in a vesicle called a phagosome. then An electron pump brings protons (H+) into the phagosome. This lowers the pH within the phagosome so that when a lysosome fuses with the phagosome, the pH is correct for the acid hydrolases to effectively break down cellular proteins., 3. destruction extracellular destruction The phagocyte will empty the contents of its lysosomes in order to kill the microorganisms or cells extracellularly., 1. attachment of microbe to phagocyte enhanced attachment attachment of microbes to phagocytes by way of an antibody molecule called IgG or complement pathways proteins called C3b and C4b, the complement pathways types alternative complement pathway, 2. ingestion process Polymerization and then depolymerization of actin filaments send pseudopods out to engulf the microbe and place it in a vesicle called a phagosome., opsonization (enhanced attachment) role in body defense The complement proteins C3b and C4b are known as opsonins because they bind microbes to phagocytes., Overview of Phagocytosis and the Complement Pathways overview of phagocytosis phagocytosis, phagocytosis steps in phagocytosis 2. ingestion, the complement pathways types classical complement pathway, inflammation role in body defense Body defense cells and defense chemicals leave the blood and enter the tissue around an injured or infected site., the complement pathways benefits of proteins from the complement pathways inflammation, MAC lysis of biological membranes role in body defense A series of complement proteins known as the membrane attack complex or MAC put pores in cellular membranes resulting in lysis.
