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This Concept Map, created with IHMC CmapTools, has information related to: Answers_Antigens, non-infectious materials examples the body's own cells that the body fails to recognize as "normal self", non-infectious materials examples foreign tissues and cells from transplants and transfusions, have B-cell receptors the B-cell receptor composed of 4 glycoprotein chains; the actually antibody molecules made by that cell and anchored to the outer surface of its cytoplasmic membrane, Each different B-lymphocyte and T-lymphocyte becomes genetically programmed to produce a B-cell receptor or T-cell receptor with a unique three-dimensional shape. clones of lymphocytes The body produces 10,000,000 or more distinct clones of both B-lymphocytes and T-lymphocytes, each with a unique B-cell receptor or T-cell receptor., Antigens substances that act as antigens infectious materials, Antigens substances that act as antigens non-infectious materials, have B-cell receptors the B-cell receptor can bind directly to epitopes on peptide, protein, polysaccharide, nucleic acid, and lipid antigens, Antigens immunogen an antigen that is recognized by the body as non-self and stimulates an adaptive immune response, Antigens epitope the actual portions of an antigen that react with receptors on B-lymphocytes and T-lymphocytes, as well as with free antibody molecules, Antigens chemical nature proteins (including conjugated proteins such as glycoproteins, lipoproteins, and nucleoproteins), The body recognizes an antigen as foreign when epitopes of that antigen bind to B-lymphocytes and T-lymphocytes by means of epitope-specific receptor molecules having a shape complementary to that of the epitope uniqueness of B-cell and T-cell receptors Each different B-lymphocyte and T-lymphocyte becomes genetically programmed to produce a B-cell receptor or T-cell receptor with a unique three-dimensional shape., Antigens antigen a substance that reacts with antibody molecules and antigen receptors on lymphocytes, Antigens hapten A small molecule that by itself is not immunogenic but can act as an antigen when it binds to a larger protein molecule., infectious materials examples microbial structures, The body recognizes an antigen as foreign when epitopes of that antigen bind to B-lymphocytes and T-lymphocytes by means of epitope-specific receptor molecules having a shape complementary to that of the epitope B-lymphocytes have B-cell receptors, Antigens recognizing an antigen as foreign The body recognizes an antigen as foreign when epitopes of that antigen bind to B-lymphocytes and T-lymphocytes by means of epitope-specific receptor molecules having a shape complementary to that of the epitope, the actual portions of an antigen that react with receptors on B-lymphocytes and T-lymphocytes, as well as with free antibody molecules polysaccharide antigens have many epitopes, but all of the same specificity, Antigens chemical nature polysaccharides (including lipopolysaccharides), the body's own cells that the body fails to recognize as "normal self" examples cancer cells, infected cells, cells involved in autoimmune diseases, have T-cell receptors the T-cell receptor can only recognize peptide epitopes from protein antigens presented by the body's own cells by way of special molecules called MHC molecules
