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This Concept Map, created with IHMC CmapTools, has information related to: Answers_SARS-CoV-2, Small subgenomic mRNAs coding for the N protein are translated by cytoplasmic ribosomes where they then bind to the genomic (+) ss RNAs to form viral nucleocapsids. Small subgenomic mRNAs coding for viral structural protein such as the S, M, and E proteins are translated at the ribosomes of the rough endoplasmic reticulum (ER) where they enter the ER. N proteins ????, nucleocapsid N or nucleocapsid protein Structurally is bound to RNA genome. involved in various processes related to viral replication., Severe Acute Respiratory Syndrome Coronavirus-2 or SARS-CoV-2 viral replication adsorption, E or envelope protein function Plays a role in the production, maturation, and release of this virus., M or membrane protein function Central organizer for coronavirus assembly., S or spike protein function S1 subunit is responsible for virus binding to ACE-2 enzyme during viral adsorption. S2 subunit is responsible for viral envelope-host cell membrane fusion during viral entry into the host cell., Coronaviruses: Enveloped single-stranded RNA viruses examples 4 species, Coronaviruses: Enveloped single-stranded RNA viruses examples Middle East Respiratory Syndrome Coronavirus or MERS-CoV, viral penetration next genome replication and production of viral mRNAs, Severe Acute Respiratory Syndrome Coronavirus-2 or SARS-CoV-2 viral structure nucleocapsid, envelope derived from host cell membranes envelope proteins E or envelope protein, adsorption next viral penetration, RNA-dependent RNA polymerase enzymes copy the antisense (-) RNA strand into (+) viral mRNAs. The (+) viral mRNA can then be translated into viral proteins by host cell ribosomes. translation of viral mRNAs Many small subgenomic RNA strands enable transcription of several subgenomic mRNAs of varying length coding for various viral proteins such as S, M, E, and N proteins., Severe Acute Respiratory Syndrome Coronavirus-2 or SARS-CoV-2 viral structure envelope derived from host cell membranes, genome replication and production of viral mRNAs ???? RNA-dependent RNA polymerase copiesy the sense (+) RNA genome producing antisense ss (-) RNA. RNA-dependent RNA polymerase enzymes then copies the antisense (-) RNA strands producing copies of the sense ss (+) RNA viral genomes., envelope derived from host cell membranes envelope proteins M or membrane protein, Coronaviruses: Enveloped single-stranded RNA viruses examples Severe Acute Respiratory Syndrome Coronavirus-2 or SARS-CoV-2, 4 species cause mild, cold-like symptoms, Coronaviruses: Enveloped single-stranded RNA viruses examples Severe Acute Respiratory Syndrome Coronavirus or SARS-CoV, genome replication and production of viral mRNAs ???? RNA-dependent RNA polymerase enzymes copy the antisense (-) RNA strand into (+) viral mRNAs. The (+) viral mRNA can then be translated into viral proteins by host cell ribosomes.
