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This Concept Map, created with IHMC CmapTools, has information related to: Answers_complement_pathways, C5b binds to the target cell and subsequently binds C6, C7, C8, and a number of monomers of C9 to form C5b6789n, the Membrane Attack Complex (MAC) benefit lysis of membrane-bound cells, C3b joins C4b2a to form a C5 convertase then C5 convertase splits C5 molecules into C5a and C5b, C3b binds to antigen as an opsonin benefit enhanced attachment of antigen to phagocytes, C5 convertase splits C5 molecules into C5a and C5b function C5a triggers inflammation, Fab of IgG or IgM binds to epitopes of an antigen finally The C1q of the C1 complex binds to either the Fc portion of IgG or IgM, the microbe, or the CRP., C3 convertase splits C3 molecules into C3a and C3b then C3b joins C4b2a to form a C5 convertase, C5a is a chemoattractant for phagocytes benefit attracts phagocytes to the infection site, C5 convertase splits C5 molecules into C5a and C5b function C5a is a chemoattractant for phagocytes, C4b and C2a combine to form C3 convertase then C3 convertase splits C3 molecules into C3a and C3b, Activated MASP2 then cleaves C4 into C4a and C4b. function C4b binds to antigen as an opsonin, factor B combines with the cell-bound C3b to form C3bB then factor D splits factor B into Bb and Ba, forming C3bBb, C3 convertase splits C3 molecules into C3a and C3b function C3a triggers inflammation, C5b binds to the target cell and subsequently binds C6, C7, C8, and a number of monomers of C9 to form C5b6789n, the Membrane Attack Complex (MAC) benefit lysis of membrane-bound cells, C4b and C2a join to form a C3 convertase then C3 convertase splits C3 molecules into C3a and C3b, C3 convertase splits C3 molecules into C3a and C3b then C3b binds to the C3bBb to form C3bBb3b, a C5 convertase, The Complement Pathways type the lectin pathway, factor D splits factor B into Bb and Ba, forming C3bBb finally properdin then binds to the Bb to form C3bBbP that functions as a C3 convertase, C3 convertase splits C3 molecules into C3a and C3b function C3b binds to antigen as an opsonin, activated C1s enzymatically cleaves C4 into C4a and C4b function C4a triggers inflammation, The Complement Pathways type the classical complement pathway