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This Concept Map, created with IHMC CmapTools, has information related to: Blanks_PRRs, Bind specifically to conserved portions of PAMPs and DAMPs DAMPs Damage-Associated Molecular Patterns, locations of signaling PRRs, signaling PRRs found in the membranes of endosomes (phagolysosomes) examples, examples, signaling PRRs found in the membranes of endosomes (phagolysosomes) examples TLR-7 and TLR-8, inflammatory cytokines examples, CD4 function promotes the ability of TLR-4 to respond to LPS, soluble molecules produced as a part of the body's immune defenses that bind microbes to phagocytes examples mannose-binding lectin, locations of signaling PRRs signaling PRRs found on cell surfaces, location found on the surface of phagocytic cells, Bind specifically to conserved portions of PAMPs and DAMPs PAMPs Pathogen-Associated Molecular Patterns, Pattern-Recognition Receptors (PRRs) examples of cells with PRRs mucosal epithelial cells, binds to double-stranded viral RNA, signaling PRRs found on cell surfaces general function, promotes the production of, binds to peptidoglycan, bacterial lipoproteins, lipoteichoic acid, and porins, binds to lipopolysaccharide, fungal mannans, viral envelope proteins, parasitic phospholipids, heat-shock proteins, benefit activates the lectin complement pathway, mannan-binding lectin binds to, examples mannose receptors
