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This Concept Map, created with IHMC CmapTools, has information related to: Answers_APCs, MHC-II/peptide complexes can then be recognized by complementary shaped T-cell receptors (TCRs) and CD4 molecules on an effector T4-lymphocytes results in effector T4-lymphocyte producing cytokines that enable that B-lymphocyte to proliferate and differentiate into antibody-secreting plasma cells, T8-effector cells examples cytotoxic T-lymphocytes (CTLs), T4-effector cells examples Treg cells, B-lymphocytes function capture and present epitopes of exogenous antigens to effector T-lymphocytes, macrophages function capture and present epitopes of exogenous antigens to effector T-lymphocytes, The peptides are transported into the vesicles containing MHC-II molecules where they bind to the MHC-II groove and eventually interact with the T-cell receptors (TCRs) and CD4 molecules on naive T4-lymphocytes. results in activation of that naive T4-lymphocyte, Antigen-Presenting Cells (APCs) functions capture and process antigens for presentation to T-lymphocytes, T4-effector cells examples TH1 cells, MHC-II molecules present epitopes of exogenous antigens to naive T4-lymphocytes mechanism MHC-II/peptide complexes can then be recognized by complementary shaped T-cell receptors (TCRs) and CD4 molecules on naive T4-lymphocytes, macrophages location throughout the body, capture and present epitopes of exogenous antigens to effector T-lymphocytes mechanism MHC-II/peptide complexes can then be recognized by complementary shaped T-cell receptors (TCRs) and CD4 molecules on an effector T4-lymphocytes, T4-effector cells examples TH2 cells, dendritic cells function capture and present epitopes of antigen to the everchanging populations of naive T8-lymphocytes and naive T4-lymphocytes in the lymph nodes, Antigen-Presenting Cells (APCs) functions produce signals required for the proliferation and differentiation of lymphocytes, capture and present epitopes of antigen to the everchanging populations of naive T8-lymphocytes and naive T4-lymphocytes in the lymph nodes MHC-I molecules MHC-I molecules present epitopes of endogenous antigens to naive T8-lymphocytes, activation of that naive T8-lymphocyte replication and differentiation into T8-effector cells, The peptides are transported into the vesicles containing MHC-I molecules where they bind to the MHC-I groove and eventually interact with the T-cell receptors (TCRs) and CD8 molecules on naive T8-lymphocytes. results in activation of that naive T8-lymphocyte, MHC-II/peptide complexes can then be recognized by complementary shaped T-cell receptors (TCRs) and CD4 molecules on an effector T4-lymphocytes results in activation of macrophage, MHC-II molecules can also bind peptide epitopes from endogenous antigens through cross-presentation by certain dendritic cells phagocytosis Exogenous antigens are phagocytosed and are degraded into protein antigens and peptide epitopes within the phagolysome. From here the antigens enter the cytoplasm and are processed by proteasomes and enter the ER or directly enter vesicles containing MHC-I molecules., capture and present epitopes of antigen to the everchanging populations of naive T8-lymphocytes and naive T4-lymphocytes in the lymph nodes MHC-II molecules MHC-II molecules can also bind peptide epitopes from endogenous antigens through cross-presentation by certain dendritic cells
