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This Concept Map, created with IHMC CmapTools, has information related to: Answers_Antigens, Antigens immunogen an antigen that is recognized by the body as non-self and stimulates an adaptive immune response, non-infectious materials examples allergens, Antigens chemical nature polysaccharides (including lipopolysaccharides), The body recognizes an antigen as foreign when epitopes of that antigen bind to B-lymphocytes and T-lymphocytes by means of epitope-specific receptor molecules having a shape complementary to that of the epitope uniqueness of B-cell and T-cell receptors Each different B-lymphocyte and T-lymphocyte becomes genetically programmed to produce a B-cell receptor or T-cell receptor with a unique three-dimensional shape., infectious materials examples microbial toxins, The body recognizes an antigen as foreign when epitopes of that antigen bind to B-lymphocytes and T-lymphocytes by means of epitope-specific receptor molecules having a shape complementary to that of the epitope B-lymphocytes have B-cell receptors, non-infectious materials examples the body's own cells that the body fails to recognize as "normal self", the actual portions of an antigen that react with receptors on B-lymphocytes and T-lymphocytes, as well as with free antibody molecules protein antigens have many epitopes of different specificities, have T-cell receptors the T-cell receptor composed of just two glycoprotein chains, Antigens substances that act as antigens infectious materials, the body's own cells that the body fails to recognize as "normal self" examples cancer cells, infected cells, cells involved in autoimmune diseases, Antigens types of antigens autoantigens, Antigens types of antigens endogenous antigens, Antigens substances that act as antigens non-infectious materials, have B-cell receptors the B-cell receptor composed of 4 glycoprotein chains; the actually antibody molecules made by that cell and anchored to the outer surface of its cytoplasmic membrane, have B-cell receptors the B-cell receptor can bind directly to epitopes on peptide, protein, polysaccharide, nucleic acid, and lipid antigens, non-infectious materials examples foreign tissues and cells from transplants and transfusions, infectious materials examples microbial structures, Antigens hapten A small molecule that by itself is not immunogenic but can act as an antigen when it binds to a larger protein molecule., The body recognizes an antigen as foreign when epitopes of that antigen bind to B-lymphocytes and T-lymphocytes by means of epitope-specific receptor molecules having a shape complementary to that of the epitope T-lymphocytes have T-cell receptors
