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This Concept Map, created with IHMC CmapTools, has information related to: Answers_T-lymphocytes, Invarient Natural Killer T-lymphocytes (iNKT Cells) (Discussed under innate immunity in Unit 4) key surface molecules T-cell receptors (TCRs), Treg cells function help to combat autoimmunity, recognize peptides from endogenous antigen bound to MHC-I molecules on the surface of all nucleated cells first step naive T8-lymphocytes, T-cell receptors (TCRs) and CD4 molecules function recognize peptides from exogenous antigen bound to MHC-II molecules on the surface of antigen-presenting cells (APCs), recognize peptides from exogenous antigen bound to MHC-II molecules on the surface of antigen-presenting cells (APCs) examples B-lymphocytes, used by the body to regulate both humoral immunity and cell-mediated immunity through cytokines they produce examples of T4-effector lymphocytes Treg cells, their differentiation into an effector T8-lymphocytes examples of effector T8-lymphocytes cytotoxic T-lymphocytes (CTLs), naive T4-lymphocytes are T4-lymphocytes that have not yet reacted with an epitope of an antigen., Treg cells function promote anamnestic response, Each T-lymphocyte becomes genetically programmed through a series of gene-splicing reactions to produce a T-cell receptor (TCR) with a unique specificity for binding a specific epitope. clones of T-lymphocytes The body produces 10,000,000 or more distinct clones of T-lymphocytes, each with a unique T-cell receptor, recognize peptides from exogenous antigen bound to MHC-II molecules on the surface of antigen-presenting cells (APCs) first step naive T4-lymphocytes, T8-lymphocytes (T8-Cells; CD8+Cells; Cytotoxic T-Lymphocytes) key surface molecules T-cell receptors (TCRs) and CD8 molecules, T4-lymphocytes that have not yet reacted with an epitope of an antigen. become activated by antigen-presenting dendritic cells, TH2 cells produce cytokines that promote the removal of microbes in mucosal tissues, TCR of iNKT cells recognize endogenous glycolipid antigen presented by CD1d molecules on antigen-presenting cells (APCs) functions produce large quantities of both TH1 cell and TH2 cell cytokines, TH2 cells produce cytokines that enable activated T-lymphocytes to rapidly proliferate and differentiate into effector cells, Treg cells function Produce inhibitory cytokines such as Interleukin-10 (IL-10) and TGF-β that help to limit immune responses and prevent autoimmunity by suppressing T-lymphocyte activity., naive T8-lymphocytes are T8-lymphocytes that have not yet reacted with an epitope of an antigen., TH2 cells produce cytokines that block the production of T1 cells, T-lymphocytes types Invarient Natural Killer T-lymphocytes (iNKT Cells) (Discussed under innate immunity in Unit 4)
