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This Concept Map, created with IHMC CmapTools, has information related to: Answers_immunodeficiency, Secondary Immunodeficiency examples of causes irradiation, conventional immunodeficiencies types Innate immunity disorders, B-lymphocyte disorders examples agammaglobulinemias, Combined B- and T-lymphocyte Disorders (Severe Combined Immunodeficiency Disease or SCID) examples defects in nucleotide salvage pathways, familial hemophagocytic lymphohistiocytosis description uncontrolled activation of macrophages and CTLs, Combined B- and T-lymphocyte Disorders (Severe Combined Immunodeficiency Disease or SCID) examples defective thymus development, Secondary Immunodeficiency examples of causes removal of spleen, novel immunodeficiencies description common, less severe primary immunodeficiencies involving just one or more of the huge number of genes involved in the immune responses, defective thymus development description no thymus for T-lymphocyte maturation, T-lymphocyte disorders examples MHC expression defects, Primary Immunodeficiency description an immunodeficiency that one is born with, MHC expression defects description decreased activation of T-lymphocytes, common, less severe primary immunodeficiencies involving just one or more of the huge number of genes involved in the immune responses results They involve the decreased ability to combat just a single type of infection or a narrow range of infections and relate to an individual’s own unique genetics., T-Lymphocyte signaling defects description decreased T-lymphocyte function, Secondary Immunodeficiency examples of causes malnutrition, Immunodeficiency types Primary Immunodeficiency, conventional immunodeficiencies types T-lymphocyte disorders, T-lymphocyte disorders examples familial hemophagocytic lymphohistiocytosis, cytokine-signaling defects description decreased antibody levels, Primary Immunodeficiency types conventional immunodeficiencies