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This Concept Map, created with IHMC CmapTools, has information related to: Answers_innate_adaptive.cmap, innate immunity role in defense the initial response by the body to eliminate microbes and prevent infection, early induced innate immunity examples of early induced innate immunity phagocytosis, takes several days to become protective and is designed to react with and remove a specific antigen branches humoral immunity, immediate innate immunity begins 0 - 4 hours after exposure to an infectious agent, takes several days to become protective and is designed to react with and remove a specific antigen memory usually improves upon repeated exposure to a given infection, adaptive immunity antigen-specific activated by epitopes of antigens binding to antigen receptors, early induced innate immunity examples of early induced innate immunity fever, early induced innate immunity examples of early induced innate immunity acute phase response, recognizes specific epitopes of a specific antigen of a microbe ???? epitope: The portion of an antigen that reacts with antibodies and B- and T-lymphocyte receptors, 0 - 4 hours after exposure to an infectious agent activated by soluble preformed antimicrobial molecules that circulate in the blood, our found in extracellular tissue fluids, and are secreted by epithelial cells, PAMPs binding to PRRs leads to recruitment of defense cells, cell-mediated immunity examples cytotoxic T-lymphocytes (CTLs), early induced innate immunity begins 4 - 96 hours after exposure to an infectious agent, activated by epitopes of antigens binding to antigen receptors specificity recognizes specific epitopes of a specific antigen of a microbe, takes several days to become protective and is designed to react with and remove a specific antigen branches cell-mediated immunity, PAMPs binding to PRRs specificity recognizes molecules shared by groups of related microbes, early induced innate immunity examples of early induced innate immunity inflammation, recruitment of defense cells examples of cells cells that release inflammatory mediators: leukocytes such as basophils and eosinophils; inflammatory cells in the tissue such as macrophages and mast cells, PAMPs binding to PRRs PAMP PAMP: pathogen-associated molecular patterns, adaptive immunity antigen-specific antigen: A substance that reacts with antibody molecules and antigen receptors on B- and T-lymphocytes