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This Concept Map, created with IHMC CmapTools, has information related to: Blanks_ clonal selection_memory, Clonal Selection, Clonal Expansion, and Memory clonal selection Each naive T4-lymphocyte becomes genetically programmed to make a T-cell receptor (TCR) with a unique specificity. Identical molecules of that TCR are placed on its surface where they are able to bind an epitope/MHC-II complex on an antigen-presenting dendritic cell with a corresponding shape., Each B-lymphocyte becomes genetically programmed to make an antibody with a unique antigen-binding site (Fab) through a series of gene translocations, and molecules of that antibody are put on its surface to function as the B-cell receptor. process, clonal expansion In response to cytokines, these activated T4-lymphocytes now rapidly proliferate to produce large clones of thousands of identical T4-lymphocytes., subsequent exposure to the same antigen, Clonal Selection, Clonal Expansion, and Memory clonal selection Each B-lymphocyte becomes genetically programmed to make an antibody with a unique antigen-binding site (Fab) through a series of gene translocations, and molecules of that antibody are put on its surface to function as the B-cell receptor., differentiation, systemic infection and vaccination, secondary anamnestic response, clonal expansion, In response to cytokines, these activated T4-lymphocytes now rapidly proliferate to produce large clones of thousands of identical T4-lymphocytes. differentiation Eventually this clone of T4-lymphocytes differentiates into effector T4-lymphocytes, Eventually this clone of T4-lymphocytes differentiates into effector T4-lymphocytes memory, infection of mucous membranes Plasma cells produced in the mucous membranes generally remain in the mucous membranes and secrete antibodies for only around a year., subsequent exposure to the same antigen, memory, time span It generally takes 4-5 days for a naive B-lymphocyte that has been activated to complete clonal expansion and differentiate into effector B-lymphocytes., primary response to a new antigen, Each naive T4-lymphocyte becomes genetically programmed to make a T-cell receptor (TCR) with a unique specificity. Identical molecules of that TCR are placed on its surface where they are able to bind an epitope/MHC-II complex on an antigen-presenting dendritic cell with a corresponding shape. process