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This Concept Map, created with IHMC CmapTools, has information related to: Blanks_APCs, results in, examples cytotoxic T-lymphocytes (CTLs), examples Treg cells, B-lymphocytes function capture and present epitopes of exogenous antigens to effector T-lymphocytes, macrophages function, The peptides are transported into the vesicles containing MHC-II molecules where they bind to the MHC-II groove and eventually interact with the T-cell receptors (TCRs) and CD4 molecules on naive T4-lymphocytes. results in, Antigen-Presenting Cells (APCs) functions capture and process antigens for presentation to T-lymphocytes, examples TH1 cells, MHC-II molecules present epitopes of exogenous antigens to naive T4-lymphocytes mechanism, macrophages location throughout the body, capture and present epitopes of exogenous antigens to effector T-lymphocytes mechanism, examples TH2 cells, dendritic cells function, Antigen-Presenting Cells (APCs) functions produce signals required for the proliferation and differentiation of lymphocytes, MHC-I molecules MHC-I molecules present epitopes of endogenous antigens to naive T8-lymphocytes, replication and differentiation into, The peptides are transported into the vesicles containing MHC-I molecules where they bind to the MHC-I groove and eventually interact with the T-cell receptors (TCRs) and CD8 molecules on naive T8-lymphocytes. results in, MHC-II/peptide complexes can then be recognized by complementary shaped T-cell receptors (TCRs) and CD4 molecules on an effector T4-lymphocytes results in, MHC-II molecules can also bind peptide epitopes from endogenous antigens through cross-presentation by certain dendritic cells phagocytosis, MHC-II molecules MHC-II molecules can also bind peptide epitopes from endogenous antigens through cross-presentation by certain dendritic cells