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This Concept Map, created with IHMC CmapTools, has information related to: Blanks_hypersensitivity, histamine release by the mast cell and the synthesis of other inflammatory mediators such as platelet-activating factor, leukotreins, bradykinins, prostaglandins, and cytokines that contribute to inflammation results in, histamine release by the mast cell and the synthesis of other inflammatory mediators such as platelet-activating factor, leukotreins, bradykinins, prostaglandins, and cytokines that contribute to inflammation results in, results in activation of macrophages and cytokine production, results in MAC lysis of surrounding tissue, Type IV (delayed hypersensitivity) mechanisms CTLs use their TCR/CD8 to bind to peptide epitopes bound to MHC-I on infected cells or normal cells having cross-reacting epitopes and kill them through apoptosis., These antibodies bind to the surface of host cells results in, results in massive inflammation, immediate hypersensivity types Type V (Stimulatory Hypersensitivity), histamine release by the mast cell and the synthesis of other inflammatory mediators such as platelet-activating factor, leukotreins, bradykinins, prostaglandins, and cytokines that contribute to inflammation results in, Type IV (delayed hypersensitivity) mechanisms TH2 cells produce interleukin-4 (IL-4) and interleukin-5 (IL-5) to promote extracellular killing by eosinophils and causing tissue damage., Hypersensitivity description the immune systems cause harm to the body, constriction of bronchial airways results in wheezing and difficulty in breathing, delayed hypersensitivity type Type IV (delayed hypersensitivity), The complexes pass between the endothelial cells of blood vessels - especially those in the skin, joints, and kidneys - and become trapped on the surrounding basement membrane beneath these cells. examples, immediate hypersensivity types Type I (IgE-mediated or anaphylactic-type), results in, immediate hypersensivity types Type II (antibody-dependent cytotoxicity), Type V (Stimulatory Hypersensitivity) mechanism, Type IV (delayed hypersensitivity) description, Hypersensitivity categories delayed hypersensitivity
