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This Concept Map, created with IHMC CmapTools, has information related to: Answers_General Steps_Adaptive_Immunity, role of antigen-presenting dendritic cells uses MHC-I molecules recognition of epitopes by naive T8-lymphocytes, proliferation of T8 lymphocytes differentiate into T-regulatory cells (T-reg), proliferation T4-lymphocytes and their differentiation into T4-effector cells examples of T4-effectors cells Th1 cells, The antigen must encounter the B-lymphocytes, T-lymphocytes, and antigen-presenting cells (APCs) capable of carrying out an adaptive immune response. occurs in the secondary lymphoid organs of the lymphoid system, T-regulatory cells (T-reg) benefits promote anamnestic response, Th1 cells activates cytotoxic T-lymphocytes (CTLs), The large clones of identical B-lymphocytes, T4-lymphocytes, and T8-lymphocytes now differentiate into effector cells capable of directing body defenses against the original antigen resulting in its destruction or neutralization. ???? proliferation T4-lymphocytes and their differentiation into T4-effector cells, activation of naive T4-lymphocyte leads to proliferation T4-lymphocytes and their differentiation into T4-effector cells, T-dependent antigens (most proteins) recognized by B-cell receptor (BCR), proliferation of T8 lymphocytes differentiate into cytotoxic T-lymphocytes (CTLs), the secondary lymphoid organs of the lymphoid system examples MALT, GALT, SALT, NALT, proliferation T4-lymphocytes and their differentiation into T4-effector cells examples of T4-effectors cells Th17 cells, T-independent antigens (large polysaccharides, lipids) types TI-1 antigens are pathogen- associated molecular patterns (PAMPS), proliferation T4-lymphocytes and their differentiation into T4-effector cells T4 effector cells interact with activated B-lymphocytes, T-regulatory cells (T-reg) benefits help to combat autoimmunity, TI-1 antigens are pathogen- associated molecular patterns (PAMPS) recognized by pattern-recognition receptors (PRRs), T-independent antigens (large polysaccharides, lipids) types TI-2 antigens, such as capsular polysaccharides, recognition of epitopes by naive B-lymphocytes antigen type T-independent antigens (large polysaccharides, lipids), macrophages benefit killing of ingested microbes, Naive B-lymphocytes and naive T4-lymphocytes must recognize epitopes of an antigen by means of antigen-specific receptor molecules on their surface and become activated. This is known as clonal selection. recognition of epitope role of antigen-presenting dendritic cells