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This Concept Map, created with IHMC CmapTools, has information related to: Answers_nucleoid, nucleoid significance to control of bacterial growth Fluroquinolones inhibit DNA topoisomerase enzymes needed for bacterial nucleic acid synthesis., nucleoid composition A long, single molecule of double-stranded, helical, supercoiled DNA., nucleoid replication Enzymes called DNA topoisomerases are essential in the unwinding, replication, and rewinding of the circular, supercoiled bacterial DNA., nucleoid characteristics Does not divide by mitosis., nucleoid replication Strand separation and complementary base pairing., nucleoid significance to control of bacterial growth Sulfamethoxazole and trimethoprim block enzymes in the bacteria pathway required for the synthesis of tetrahydrofolic acid, a cofactor needed for bacteria to synthesize nucleotide bases., nucleoid significance to initiating innate immunity Bacterial genomes contain a high frequency of unmethylated cytosine-guanine dinucleotide sequences that are recognized as PAMPs., nucleoid composition The two ends of the double-stranded DNA covalently bond together to form both a physical and genetic circle., nucleoid characteristics The nucleoid is not surrounded by a nuclear membrane., nucleoid characteristics No nucleoli., nucleoid function DNA determines what proteins and enzymes an organism can synthesize and, therefore, what chemical reactions it is able to carry out.
