WARNING:
JavaScript is turned OFF. None of the links on this concept map will
work until it is reactivated.
If you need help turning JavaScript On, click here.
This Concept Map, created with IHMC CmapTools, has information related to: Answers_Antibiotic_Resistance, producing beta-lactamases action breaks down beta-lactam antibiotics, the bacterium stops replicating when the antibiotic is present when drug is gone once the antibiotic is no longer present, the bacterium starts replicating again, altering the target site receptor for the antibiotic to reduce or block its binding examples producing an altered 30S or 50S ribosomal subunit to which antibiotic no longer binds, alters shape of aminoglycosides examples of aminoglycosides streptomycin, neomycin, netilmicin, tobramycin, gentamicin, amikacin, mutation alters genes Gene products enable the bacterium to become resistant to an antibiotic or chemical agent., blocks active transport result antibiotic does not enter the bacterium, not producing an antisense RNA that is complementary to a mRNA leads to mRNA continues to be translated into enzyme, induces antibiotic tolerance when drug is present the bacterium stops replicating when the antibiotic is present, beta-lactam antibiotics no longer bind to transpeptidase examples of beta- lactam antibiotics penicillins, monobactams, carbapenems, cephalosporins, altering the target site receptor for the antibiotic to reduce or block its binding examples producing altered transpeptidases, Gene products enable the bacterium to become resistant to an antibiotic or chemical agent. mechanism induces antibiotic tolerance, altering the membranes and transport systems to prevent the entry of the antibiotic into the bacterium and/or actively transport the antibiotic out of the bacterium examples altering porins in the outer membrane of gram-negative cell walls, Gene products enable the bacterium to become resistant to an antibiotic or chemical agent. mechanism altering the target site receptor for the antibiotic to reduce or block its binding, producing an altered 30S or 50S ribosomal subunit to which antibiotic no longer binds example producing an altered 50S subunit to which macrolides no longer bind, producing transport proteins that actively transport the antibiotic back out of the bacterium result insufficient antibiotic within the bacterium, increased synthesis of the limited enzyme result insufficient antibiotic to tie up all the enzyme, mRNA continues to be translated into enzyme leads to increased synthesis of the limited enzyme, breaks down beta-lactam antibiotics examples of beta- lactam antibiotics penicillins, monobactams, carbapenems, cephalosporins, Gene products enable the bacterium to become resistant to an antibiotic or chemical agent. mechanism modulating gene expression to produce more of the bacterial enzyme that is being tied up or altered by the antibiotic, altering the transport proteins in the cytoplasmic membrane action blocks active transport
