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This Concept Map, created with IHMC CmapTools, has information related to: Answers_Colonization, Virulence Factors that Promote Bacterial Colonization of the Host often a result of Quorum Sensing, The production, release, and community-wide sensing of molecules called autoinducers that modulate gene expression in response to the density of a bacterial population process Autoinducers produced by one bacterium cross the membrane of another and bind to receptors in its cytoplasm., Quorum Sensing definition The production, release, and community-wide sensing of molecules called autoinducers that modulate gene expression in response to the density of a bacterial population, In order for most bacteria to cause infectious disease or become normal flora of the body they must have the ability to colonize the body, that is, to establish themselves in or on the body and not be completely removed. colonization virulence factors The ability to compete for nutrients such as iron, Autoinducers produced by one bacterium cross the membrane of another and bind to receptors in its cytoplasm. then Autoinducer/receptor complexes are able to bind to DNA promoters and activate the transcription of quorum sensing-controlled genes., Autoinducer/receptor complexes are able to bind to DNA promoters and activate the transcription of quorum sensing-controlled genes. benefit Individual bacteria within a group are able to benefit from the activity of the entire group., In order for most bacteria to cause infectious disease or become normal flora of the body they must have the ability to colonize the body, that is, to establish themselves in or on the body and not be completely removed. colonization virulence factors The ability to invade host cells, In order for most bacteria to cause infectious disease or become normal flora of the body they must have the ability to colonize the body, that is, to establish themselves in or on the body and not be completely removed. colonization virulence factors The ability to resist innate immunity, In order for most bacteria to cause infectious disease or become normal flora of the body they must have the ability to colonize the body, that is, to establish themselves in or on the body and not be completely removed. colonization virulence factors Using motility and other means to contact host cells and disseminate within a host, Virulence Factors that Promote Bacterial Colonization of the Host colonization of the body In order for most bacteria to cause infectious disease or become normal flora of the body they must have the ability to colonize the body, that is, to establish themselves in or on the body and not be completely removed., Virulence Factors that Promote Bacterial Colonization of the Host virulence genes Most genes coding for virulence factors in bacteria are located in pathogenicity islands or PAIs and are usually acquired by horizontal gene transfer involving conjugative plasmids., In order for most bacteria to cause infectious disease or become normal flora of the body they must have the ability to colonize the body, that is, to establish themselves in or on the body and not be completely removed. colonization virulence factors The ability to resist Adaptive immunity, In order for most bacteria to cause infectious disease or become normal flora of the body they must have the ability to colonize the body, that is, to establish themselves in or on the body and not be completely removed. colonization virulence factors The ability to adhere to host cells and resist physical removal