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This Concept Map, created with IHMC CmapTools, has information related to: Answers_phago_comp, the complement pathways benefits of proteins from the complement pathways inflammation, the complement pathways benefits of proteins from the complement pathways phagocyte chemotaxis, phagocytosis steps in phagocytosis 3. destruction, the complement pathways types classical complement pathway, the complement pathways benefits of proteins from the complement pathways opsonization (enhanced attachment), opsonization (enhanced attachment) role in body defense The complement proteins C3b and C4b are known as opsonins because they bind microbes to phagocytes., Overview of Phagocytosis, Antibacterial Peptides, and the Complement Pathways overview of the complement pathways the complement pathways, the complement pathways types alternative complement pathway, Polymerization and then depolymerization of actin filaments send pseudopods out to engulf the microbe and place it in a vesicle called a phagosome. then An electron pump brings protons (H+) into the phagosome. This lowers the pH within the phagosome so that when a lysosome fuses with the phagosome, the pH is correct for the acid hydrolases to effectively break down cellular proteins., phagocytosis steps in phagocytosis 1. attachment of microbe to phagocyte, phagocytosis steps in phagocytosis 2. ingestion, Overview of Phagocytosis, Antibacterial Peptides, and the Complement Pathways antibacterial peptides Directly toxic by forming pores in the cytoplasmic membrane of a variety of microorganisms causing leakage of cellular needs., MAC lysis of biological membranes role in body defense A series of complement proteins known as the membrane attack complex or MAC put pores in cellular membranes resulting in lysis., phagocyte chemotaxis role in body defense enables the phagocytes to move toward the infected area in order to remove microorganisms, the complement pathways benefits of proteins from the complement pathways MAC lysis of biological membranes, Overview of Phagocytosis, Antibacterial Peptides, and the Complement Pathways overview of phagocytosis phagocytosis, 3. destruction extracellular destruction The phagocyte will empty the contents of its lysosomes in order to kill the microorganisms or cells extracellularly., 3. destruction intracellular destruction Lysosomes, containing digestive enzymes and microbicidal chemicals, fuse with the phagosome containing the ingested microbe and the microbe is destroyed., 2. ingestion process Polymerization and then depolymerization of actin filaments send pseudopods out to engulf the microbe and place it in a vesicle called a phagosome., 1. attachment of microbe to phagocyte enhanced attachment attachment of microbes to phagocytes by way of an antibody molecule called IgG or complement pathways proteins called C3b and C4b
