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This Concept Map, created with IHMC CmapTools, has information related to: Answers_type III toxins, Shiga toxin produced by Shigella species, enterohemorrhagic Escherichia coli (EHEC), Enterotoxins mode of action Cause loss of electrolytes and water resulting in diarrhea, Diphtheria exotoxin produced by Corynebacterium diphtheriae, Type III Toxins (AB Toxins and Other Toxins that Interfere with Host Cell Functions) AB toxins Pertussis exotoxin, Type III Toxins (AB Toxins and Other Toxins that Interfere with Host Cell Functions) other toxins Tetanus exotoxin, Tetanus exotoxin mode of action Blocks the release of inhibitors of contraction keeping the involved muscles in a state of contraction, Type III Toxins (AB Toxins and Other Toxins that Interfere with Host Cell Functions) AB toxins B or binding component that binds the exotoxin to a receptor molecule on the surface of the host cell membrane and determines the type of host cell to which the toxin is able to affect, Type III Toxins (AB Toxins and Other Toxins that Interfere with Host Cell Functions) AB toxins A or active component that enzymatically inactivates some host cell intracellular target or signaling pathway to interfere with a host cell function, Shiga toxin mode of action Stops host cell protein synthesis; ulceration of the colon; hemolytic uremic syndrome (HUS), Cholera exotoxin produced by Vibrio cholerae, Cholera exotoxin mode of action Causes loss of fluids, diarrhea, and severe dehydration, Type III Toxins (AB Toxins and Other Toxins that Interfere with Host Cell Functions) AB toxins Enterotoxins, Type III Toxins (AB Toxins and Other Toxins that Interfere with Host Cell Functions) AB toxins Shiga toxin, Type III Toxins (AB Toxins and Other Toxins that Interfere with Host Cell Functions) AB toxins Cholera exotoxin, Type III Toxins (AB Toxins and Other Toxins that Interfere with Host Cell Functions) AB toxins Diphtheria exotoxin, Pertussis exotoxin produced by Bordetella pertussis, Diphtheria exotoxin mode of action Interferes with host cell protein synthesis, Blocks the release of inhibitors of contraction keeping the involved muscles in a state of contraction results in spastic paralysis, Removes the ADP-ribosyl group from the coenzyme NAD and covalently attach it to some host cell protein (ADP- ribosylation) result Interferes with the normal function of that particular host cell protein, Botulinal exotoxin mode of action Blocks the release of acetylcholine at nerve synapses inhibiting muscle contraction
