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This Concept Map, created with IHMC CmapTools, has information related to: Answers_Enveloped_Virus _Life_Cycle, The viral envelope may fuse with the host cell cytoplasmic membrane and the nucleocapsid is released into the cytoplasm. step-3 Viral movement to the site of replication within the host cell and release of the viral genome from the remainder of the virus, Most viruses with an RNA genome replicate in the cytoplasm. step-4 Replication: The viral genome directs the host cell's metabolic machinery to synthesize viral enzymes and viral parts. The viral genome has to both replicate itself and become transcribed into viral mRNA molecules. The viral mRNA can then be translated by the host cell's ribosomes into viral structural components and enzymes need for replication and assembly of the virus., Viral movement to the site of replication within the host cell and release of the viral genome from the remainder of the virus method Lysis of endosome, Viral release from the host cell budding Viruses obtaining their envelope from the cytoplasmic membrane are released during the budding process., Release of genome from the capsid site of replication Most viruses with an RNA genome replicate in the cytoplasm., Viral entry or penetration: All or part of the virus enters the host cell. fusion The viral envelope may fuse with the host cell cytoplasmic membrane and the nucleocapsid is released into the cytoplasm., The host cell cytoplasmic membrane invaginates and pinches off, placing the entire virus in an endocytic vesicle. step-3 Viral movement to the site of replication within the host cell and release of the viral genome from the remainder of the virus, Release of genome from the capsid DNA genome Most viruses with a DNA genome enter the nucleus of the host cell., Productive life cycle of enveloped animal viruses step-1 Adsorption: Attachment sites on the viral envelope bind or adsorb to receptor sites on the host cell's cytoplasmic membrane., Adsorption: Attachment sites on the viral envelope bind or adsorb to receptor sites on the host cell's cytoplasmic membrane. step-2 Viral entry or penetration: All or part of the virus enters the host cell., Most viruses with an RNA genome replicate in the cytoplasm. step-4 Replication: The viral genome directs the host cell's metabolic machinery to synthesize viral enzymes and viral parts. The viral genome has to both replicate itself and become transcribed into viral mRNA molecules. The viral mRNA can then be translated by the host cell's ribosomes into viral structural components and enzymes need for replication and assembly of the virus., The viral capsid interacts with the nuclear membrane enabling the viral DNA genome to enter the nucleus through the pores in the nuclear membrane. step-4 Replication: The viral genome directs the host cell's metabolic machinery to synthesize viral enzymes and viral parts. The viral genome has to both replicate itself and become transcribed into viral mRNA molecules. The viral mRNA can then be translated by the host cell's ribosomes into viral structural components and enzymes need for replication and assembly of the virus., Release of genome from the capsid RNA genome Most viruses with an RNA genome replicate in the cytoplasm., Viral movement to the site of replication within the host cell and release of the viral genome from the remainder of the virus DNA genome Release of genome from the capsid, Release of genome from the capsid site of replication Most viruses with a DNA genome enter the nucleus of the host cell., Most viruses with a DNA genome enter the nucleus of the host cell. method of entry The viral DNA genome is released from the capsid, enters the cytoplasm of the host cell, and enters the nucleus through the pores in the nuclear membrane., The nucleocapsid of small DNA viruses enters the nucleus and the capsid is removed, releasing the viral DNA genome into the nucleoplasm. step-4 Replication: The viral genome directs the host cell's metabolic machinery to synthesize viral enzymes and viral parts. The viral genome has to both replicate itself and become transcribed into viral mRNA molecules. The viral mRNA can then be translated by the host cell's ribosomes into viral structural components and enzymes need for replication and assembly of the virus., The viral DNA genome is released from the capsid, enters the cytoplasm of the host cell, and enters the nucleus through the pores in the nuclear membrane. step-4 Replication: The viral genome directs the host cell's metabolic machinery to synthesize viral enzymes and viral parts. The viral genome has to both replicate itself and become transcribed into viral mRNA molecules. The viral mRNA can then be translated by the host cell's ribosomes into viral structural components and enzymes need for replication and assembly of the virus., Viral release from the host cell exocytosis Viruses obtaining their envelopes from the membranes of the nucleus, the endoplasmic reticulum, or the Golgi apparatus are then released by exocytosis via transport vesicles., Most viruses with a DNA genome enter the nucleus of the host cell. method of entry The viral capsid interacts with the nuclear membrane enabling the viral DNA genome to enter the nucleus through the pores in the nuclear membrane.