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This Concept Map, created with IHMC CmapTools, has information related to: Answers_Naked_Virus _Life_Cycle, The viral DNA genome enters the nucleus through the pores in the nuclelear membrane. step-4 Replication: The viral genome directs the host cell's metabolic machinery to synthesize viral enzymes and viral parts. The viral genome has to both replicate itself and become transcribed into viral mRNA molecules. The viral mRNA can then be translated by the host cell's ribosomes into viral structural components and enzymes need for replication and assembly of the virus., The viral capsid interacts with the nuclear membrane enabling the viral DNA genome to enter the nucleus through the pores in the nuclear membrane. step-4 Replication: The viral genome directs the host cell's metabolic machinery to synthesize viral enzymes and viral parts. The viral genome has to both replicate itself and become transcribed into viral mRNA molecules. The viral mRNA can then be translated by the host cell's ribosomes into viral structural components and enzymes need for replication and assembly of the virus., If the viral genome is RNA, it is released from the capsid and enters the cytoplasm of the host cell. method Capsid and receptor rearrangement, Viral assembly or maturation: The viral capsid assembles around the viral genome. step-6 Viral release from the host cell: Naked viruses are predominantly released by host cell lysis., The viral DNA genome is released from the capsid, enters the cytoplasm of the host cell, and enters the nucleus through the pores in the nuclear membrane. step-4 Replication: The viral genome directs the host cell's metabolic machinery to synthesize viral enzymes and viral parts. The viral genome has to both replicate itself and become transcribed into viral mRNA molecules. The viral mRNA can then be translated by the host cell's ribosomes into viral structural components and enzymes need for replication and assembly of the virus., Viral entry or penetration: All or part of the virus enters the host cell. fusion Rearrangement of capsid proteins and the host cell receptor allows the viral nucleic acid to pass through the host cell's membrane., Rearrangement of capsid proteins and the host cell receptor allows the viral nucleic acid to pass through the host cell's membrane. step-3 The viral genome moves to the site of replication within the host cell., The viral genome moves to the site of replication within the host cell. type of genome Most viruses with an RNA genome replicate in the cytoplasm., Most viruses with a DNA genome enter the nucleus of the host cell. method of entry The viral DNA genome is released from the capsid, enters the cytoplasm of the host cell, and enters the nucleus through the pores in the nuclear membrane., Viral movement to the site of replication within the host cell and release of the viral genome from the remainder of the virus. type of genome Most viruses with a DNA genome enter the nucleus of the host cell., Productive life cycle of naked animal viruses. step-1 Adsorption: Attachment sites on the viral surface bind or adsorb to receptor sites on the host cell's cytoplasmic membrane., Viral movement to the site of replication within the host cell and release of the viral genome from the remainder of the virus. type of genome If the viral genome is RNA, it is released from the capsid and enters the cytoplasm of the host cell., Adsorption: Attachment sites on the viral surface bind or adsorb to receptor sites on the host cell's cytoplasmic membrane. step-2 Viral entry or penetration: All or part of the virus enters the host cell., Most viruses with an RNA genome replicate in the cytoplasm. step-4 Replication: The viral genome directs the host cell's metabolic machinery to synthesize viral enzymes and viral parts. The viral genome has to both replicate itself and become transcribed into viral mRNA molecules. The viral mRNA can then be translated by the host cell's ribosomes into viral structural components and enzymes need for replication and assembly of the virus., If the viral genome is RNA, it is released from the capsid and enters the cytoplasm of the host cell. method Lysis of endosome, Release of genome from capsid site of replication Capsid and receptor rearrangement, Most viruses with an RNA genome replicate in the cytoplasm. step-4 Replication: The viral genome directs the host cell's metabolic machinery to synthesize viral enzymes and viral parts. The viral genome has to both replicate itself and become transcribed into viral mRNA molecules. The viral mRNA can then be translated by the host cell's ribosomes into viral structural components and enzymes need for replication and assembly of the virus., The nucleocapsid of small DNA viruses enters the nucleus and the capsid is removed, releasing the viral DNA genome into the nucleoplasm. step-4 Replication: The viral genome directs the host cell's metabolic machinery to synthesize viral enzymes and viral parts. The viral genome has to both replicate itself and become transcribed into viral mRNA molecules. The viral mRNA can then be translated by the host cell's ribosomes into viral structural components and enzymes need for replication and assembly of the virus., Viral entry or penetration: All or part of the virus enters the host cell. receptor-mediated endocytosis The host cell cytoplasmic membrane invaginates and pinches off, placing the virus in an endocytic vesicle., Most viruses with a DNA genome enter the nucleus of the host cell. method of entry The nucleocapsid of small DNA viruses enters the nucleus and the capsid is removed, releasing the viral DNA genome into the nucleoplasm.
animation showing a viral DNA genome entering the nucleus of the host cell through the pores in the nuclear membrane
Animation of the maturation of a naked virus: Not Found
Replication of a Double-Stranded DNA Viral Genome and production of Viral mRNA
Replication of a Single-Stranded DNA Viral Genome and Production of Viral mRNA
Replication of a Double-Stranded RNA Viral Genome and Production of Viral mRNA
Replication of a Single-Stranded Minus RNA Viral Genome and Production of Viral mRNA
Replication of a Single-Stranded Plus RNA Viral Genome and Production of Viral mRNA
Replication of a Single-Stranded Plus RNA Viral Genome and Production of Viral mRNA by way of Reverse Transcriptase
animation showing a viral DNA genome entering the nucleus of the host cell through the pores in the nuclear membrane
animation showing release of the viral genome from the capsid (uncoating)
animation showing maturation of a naked virus
animation showing entry of a naked virus by capsid reconfiguration
animation showing a viral capsid interacting with the nuclear membrane of the host cell enabling the viral DNA to enter the nucleus
animation showing viral capsid undergoing conformational changes that forms pores in the endocytic vesicle and enable the virial genome to enter the cytoplasm
animation showing penetration of a naked virus by endocytosis
animation showing adsorption of a naked virus
animation showing maturation of a naked virus
animation showing a viral nucleocapsid entering the nuclear membrane of the host cell
animation showing penetration of a naked virus by endocytosis
