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This Concept Map, created with IHMC CmapTools, has information related to: Answers_Cytokines_PAMPs_PRRs, hypovolemia leads to hypoperfusion, promotes body defense by stimulating an inflammatory response results in vasodilation and diapedesis, hypotension leads to hypoperfusion, acute respiratory distress syndrome (ARDS) leads to lungs can't oxygenate the blood, acidosis results stops metabolic enzyme reactions, low levels of cell wall PAMPs are released and bind to PRRs on defense cells results in moderate production of inflammatory cytokines (IL-1, IL-8, TNF-alpha NO, etc.), prolonged vasodilation results in decreased vascular resistance, high levels of cell wall PAMPs are released and bind to PRRs on defense cells results in excessive production of complement pathway proteins, excessive production of complement pathway proteins harmful effects excessive inflammation, moderate activation of the coagulation pathway benefits promotes inflammation, extracellular killing by neutrophils results in tissue damage, lungs can't oxygenate the blood leads to hypoperfusion, plugs capillaries leads to hypoperfusion, blood and plasma leaves blood and enters tissue causes acute respiratory distress syndrome (ARDS), moderate production of inflammatory cytokines (IL-1, IL-8, TNF-alpha NO, etc.) inflammatory cytokines promotes body defense by stimulating an inflammatory response, lungs can't oxygenate the blood leads to acidosis, low levels of cell wall PAMPs are released and bind to PRRs on defense cells results in moderate production of complement pathways proteins, disseminated intravascular coagulation (DIC) result plugs capillaries, Pattern-Recognition Receptors (PRRs) on macrophages, dendritic cells, and other cells. severe, systemic infection high levels of cell wall PAMPs are released and bind to PRRs on defense cells, delivers defense cells and defense chemicals to the infection site examples antibodies, defensins, lysozyme, etc.
