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This Concept Map, created with IHMC CmapTools, has information related to: Answers_APCs, dendritic cells function capture and present epitopes of antigen to the everchanging populations of naive T8-lymphocytes and naive T4-lymphocytes in the lymph nodes, T4-effector cells examples Th17 cells, Antigen-Presenting Cells (APCs) examples B-lymphocytes, capture and present epitopes of exogenous antigens to effector T-lymphocytes mechanism MHC-II/peptide complexes can then be recognized by complementary shaped T-cell receptors (TCRs) and CD4 molecules on an effector T4-lymphocytes, Antigen-Presenting Cells (APCs) MHC expression express both MHC-I and MHC-II molecules, MHC-I/peptide complexes can then be recognized by complementary shaped T-cell receptors (TCRs) and CD8 molecules on naive T8-lymphocytes results in activation of that naive T8-lymphocyte, MHC-II molecules present epitopes of exogenous antigens to naive T4-lymphocytes cross-presentation to T8-lymphocytes Certain dendritic cells are capable of cross-presentation of exogenous antigens to naive T8-lymphocytes. In this way, T8-lymphocytes can play a role in defending against both exogenous and endogenous antigens, Antigen-Presenting Cells (APCs) examples dendritic cells, B-lymphocytes location circulate back and forth between the blood and the lymphoid system of the body, MHC-II molecules present epitopes of exogenous antigens to naive T4-lymphocytes mechanism MHC-II/peptide complexes can then be recognized by complementary shaped T-cell receptors (TCRs) and CD4 molecules on naive T4-lymphocytes, T8-effector cells examples T-regulatory cells (T-regs), T8-effector cells examples T8-memory cells, capture and present epitopes of exogenous antigens to effector T-lymphocytes mechanism MHC-II/peptide complexes can then be recognized by complementary shaped T-cell receptors (TCRs) and CD4 molecules on an effector T4-lymphocytes, MHC-I molecules present epitopes of endogenous antigens to naive T8-lymphocytes cross-presentation to T4-lymphocytes Certain dendritic cells are capable of cross-presentation of endogenous antigens to naive T4-lymphocytes. In this way, T4-lymphocytes can play a role in defending against both exogenous and endogenous antigens., MHC-II/peptide complexes can then be recognized by complementary shaped T-cell receptors (TCRs) and CD4 molecules on an effector T4-lymphocytes results in effector T4-lymphocyte producing cytokines that enable that B-lymphocyte to proliferate and differentiate into antibody-secreting plasma cells, capture and present epitopes of antigen to the everchanging populations of naive T8-lymphocytes and naive T4-lymphocytes in the lymph nodes MHC-I molecules MHC-I molecules present epitopes of endogenous antigens to naive T8-lymphocytes, T4-effector cells examples T4-memory cells, macrophages location throughout the body, activation of that naive T8-lymphocyte replication and differentiation into T8-effector cells, dendritic cells location throughout the epithelium of the skin mucous membranes, as well as lymphoid tissues and organ parenchyma