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This Concept Map, created with IHMC CmapTools, has information related to: Answers_Antigens, autoantigens definition Any of an organism's own antigens (self-antigens) that stimulate an autoimmune reaction., Antigens recognizing an antigen as foreign The body recognizes an antigen as foreign when epitopes of that antigen bind to B-lymphocytes and T-lymphocytes by means of epitope-specific receptor molecules having a shape complementary to that of the epitope, Antigens substances that act as antigens non-infectious materials, Antigens types of antigens autoantigens, endogenous antigens definition Antigens found within the cytosol of human cells such as viral proteins, proteins from intracellular bacteria, and tumor antigens., Antigens antigen a substance that reacts with antibody molecules and antigen receptors on lymphocytes, exogenous antigens definition Antigens that enter from outside the body, such as bacteria, fungi, protozoa, and free viruses., non-infectious materials examples the body's own cells that the body fails to recognize as "normal self", The body recognizes an antigen as foreign when epitopes of that antigen bind to B-lymphocytes and T-lymphocytes by means of epitope-specific receptor molecules having a shape complementary to that of the epitope B-lymphocytes have B-cell receptors, the actual portions of an antigen that react with receptors on B-lymphocytes and T-lymphocytes, as well as with free antibody molecules protein antigens have many epitopes of different specificities, have B-cell receptors the B-cell receptor can bind directly to epitopes on peptide, protein, polysaccharide, nucleic acid, and lipid antigens, Antigens chemical nature polysaccharides (including lipopolysaccharides), non-infectious materials examples allergens, Antigens epitope the actual portions of an antigen that react with receptors on B-lymphocytes and T-lymphocytes, as well as with free antibody molecules, the body's own cells that the body fails to recognize as "normal self" examples cancer cells, infected cells, cells involved in autoimmune diseases, the actual portions of an antigen that react with receptors on B-lymphocytes and T-lymphocytes, as well as with free antibody molecules polysaccharide antigens have many epitopes, but all of the same specificity, have B-cell receptors the B-cell receptor composed of 4 glycoprotein chains; the actually antibody molecules made by that cell and anchored to the outer surface of its cytoplasmic membrane, infectious materials examples microbial toxins, Antigens chemical nature proteins (including conjugated proteins such as glycoproteins, lipoproteins, and nucleoproteins), Each different B-lymphocyte and T-lymphocyte becomes genetically programmed to produce a B-cell receptor or T-cell receptor with a unique three-dimensional shape. clones of lymphocytes The body produces 10,000,000 or more distinct clones of both B-lymphocytes and T-lymphocytes, each with a unique B-cell receptor or T-cell receptor.
