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This Concept Map, created with IHMC CmapTools, has information related to: Answers_B-lymphocytes, MHC-II/peptide complexes can then be recognized by complementary shaped T-cell receptors (TCRs) and CD4 molecules on an effector T4-lymphocytes result effector T4-lymphocyte producing cytokines that interact with that B-lymphocyte, the antigen is engulfed, placed in a phagosome, and degraded with lysosomes then peptide epitopes are bound to MHC-II molecules and placed on the surface of the B-lymphocyte, each B-lymphocyte becomes genetically programmed through a series of gene-splicing reactions to produce an antibody molecule with a unique specificity for binding a specific epitope subsequently molecules of that unique antibody are placed on the surface of the B-lymphocyte where they can function as B-cell receptors, peptide epitopes are bound to MHC-II molecules and placed on the surface of the B-lymphocyte antigen-presentation MHC-II/peptide complexes can then be recognized by complementary shaped T-cell receptors (TCRs) and CD4 molecules on an effector T4-lymphocytes, each B-lymphocyte becomes genetically programmed through a series of gene-splicing reactions to produce an antibody molecule with a unique specificity for binding a specific epitope B-lymphocyte clones The body produces 10,000,000 or more distinct clones of T-lymphocytes, each with a unique T-cell receptor, effector T4-lymphocyte producing cytokines that interact with that B-lymphocyte action of cytokines stimulate activated B-lymphocytes to synthesize and secrete antibodies, effector T4-lymphocyte producing cytokines that interact with that B-lymphocyte action of cytokines enable antibody producing cells to switch the class or isotype of antibodies, molecules of that unique antibody are placed on the surface of the B-lymphocyte where they can function as B-cell receptors activation initial activation of a naive B-lymphocyte occurs when B-cell receptors on the surface of the B-lymphocyte bind epitopes of an exogenous antigen having a corresponding shape., initial activation of a naive B-lymphocyte occurs when B-cell receptors on the surface of the B-lymphocyte bind epitopes of an exogenous antigen having a corresponding shape. then the antigen is engulfed, placed in a phagosome, and degraded with lysosomes, B-lymphocytes location circulate back and forth between the blood and the lymphoid system of the body, effector T4-lymphocyte producing cytokines that interact with that B-lymphocyte action of cytokines promote the differentiation of B-lymphocytes into antibody-secreting plasma cells as well as B-memory lymphocytes, B-lymphocytes maturation each B-lymphocyte becomes genetically programmed through a series of gene-splicing reactions to produce an antibody molecule with a unique specificity for binding a specific epitope, effector T4-lymphocyte producing cytokines that interact with that B-lymphocyte action of cytokines enable activated B-lymphocytes to proliferate
