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This Concept Map, created with IHMC CmapTools, has information related to: Answers_CMI, Th1 cells functions Th1 cells use their TCR and CD4 molecules to bind to the peptide/MHC-II complex on macrophages, used by the body to regulate both humoral immunity and cell-mediated immunity through cytokines they produce examples of T4-effector lymphocytes T4-memory cells, T4-memory cells function anamnestic response, activate NK cells results apoptosis of infected cells and cancer cells that suppress production of MHC-1 molecules, produce cytokines that promote cell-mediated immunity cytokines activate NK cells, Ways In Which Cell-Mediated Immunity Protects The Body by killing infected cells and cancer cells with cytotoxic T-lymphocytes (CTLs), recognize peptides from endogenous antigen bound to MHC-I molecules on the surface of all nucleated cells first step naive T8-lymphocytes, antigen-presenting dendritic cells results in proliferation of activated T4-lymphocytes, producing cytokines to promote immunity mechanism T4-Lymphocytes (T4-Helper Cells, CD4+ Cells), cytotoxic T-lymphocytes (CTLs) function CTLs use their TCR and CD8 to bind to and kill infected cells and tumor cells by inducing apoptosis, their differentiation into an effector T8-lymphocytes examples of effector T8-lymphocytes cytotoxic T-lymphocytes (CTLs), antigen-presenting dendritic cells results in their differentiation into an effector T4-lymphocyte, naive T4-lymphocytes are T4-lymphocytes that have not yet reacted with an epitope of an antigen., Ways In Which Cell-Mediated Immunity Protects The Body by producing cytokines to promote immunity, Macrophages process epitopes from endogenous antigens, attach those epitopes to MHC-II molecules, and anchor them to their cytoplasmic membrane. results in macrophages secreting inflammatory cytokines, recognize peptides from exogenous antigen bound to MHC-II molecules on the surface of antigen-presenting cells (APCs) examples macrophages, Th1 cells functions produce cytokines that promote cell-mediated immunity, activating macrophages and NK cells mechanisms activate NK cells, T4-Lymphocytes (T4-Helper Cells, CD4+ Cells) function recognize peptides from exogenous antigen bound to MHC-II molecules on the surface of antigen-presenting cells (APCs), recognize peptides from exogenous antigen bound to MHC-II molecules on the surface of antigen-presenting cells (APCs) first step naive T4-lymphocytes
