Fig. 12: DNA Replication by Complementary Base Pairing: Replacing RNA Primer with DNA

Eventually, DNA polymerase II digests away the RNA primer and replaces the RNA nucleotides of the primer with the proper DNA nucleotides to fill the gap. Finally, the DNA fragments on the lagging strand are hooked together by the enzyme DNA ligase.

Illustration of DNA Replication by Complementary Base Pairing: Replacing RNA Primer with DNA.jpg by Gary E. Kaiser, Ph.D.
Professor of Microbiology, The Community College of Baltimore County, Catonsville Campus
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at https://cwoer.ccbcmd.edu/science/microbiology/index_gos.html.

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Last updated: Feb., 2021
Please send comments and inquiries to Dr. Gary Kaiser