Fig. 1: Pairing of Homologous
DNA molecules and Exchange of
DNA Segments by way of Rec A Protein
Fig. 1: Pairing of Homologous
DNA molecules and Exchange of
DNA Segments by way of Rec A Protein
1) A DNA endonuclease inserts a nick in one strand of the donor DNA. 2) The nicked strand is separated from its partner strand by proteins functioning as a helicase. Molecules of single-stranded binding protein (yellow) then bind. 3) Rec A protein then binds to the single-strand fragment and promotes base pairing of the donor DNA with the recipient DNA (crossing over). 4) The linked molecules are separated by resolvases, enzymes that cut and rejoin the cross-linked DNA molecules.
Illustration of Pairing of Homologous
DNA molecules and Exchange of
DNA Segments by way of Rec A Protein .jpg by Gary E. Kaiser, Ph.D.
Professor of Microbiology,
The Community College of Baltimore County, Catonsville Campus
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at https://cwoer.ccbcmd.edu/science/microbiology/index_gos.html.
Last updated: August, 2018
Please send comments and inquiries to Dr.
Gary Kaiser
