Fig. 18: Mode of Action of Oxazolidinones Blocking the Attachment of the 50S Ribosomal Subunit to the Initiation Complex

The oxazolidinones (linezolid) bind to the 23S rRNA in the 50S ribosomal subunit and interfere with the formation of the initiation complex.

Illustration of Function of the Mode of Action of Oxazolidinones Blocking the Attachment of the 50S Ribosomal Subunit to the Initiation Complex.jpg
by Gary E. Kaiser, Ph.D., Professor of Microbiology, The Community College of Baltimore County, Catonsville Campus.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at https://cwoer.ccbcmd.edu/science/microbiology/index_gos.html.

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Last updated: September, 2018
Please send comments and inquiries to Dr. Gary Kaiser