BIOL 230 Lecture Guide -E. coli Inducing Pedestal Formation

Fig. 7: E. coli Using a Type 3 Secretion System to
Induce Pedestal Formation in a Host Cell

Escherichia coli O157 utilizes a type 3 secretion system to inject effector proteins into intestinal epithelial cells. Some of these cause polymerization of actin at the cell surface and this pushes the host cell cytoplasmic membrane up to form a pedestal. Another effector protein inserts into the membrane of the pedestal to serve as a receptor molecule for E. coli adhesins

Illustration of E. coli Using a Type 3 Secretion System to Induce Pedestal Formation in a Host Cell.jpg by Gary E. Kaiser, Ph.D.
Professor of Microbiology, The Community College of Baltimore County, Catonsville Campus
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at https://cwoer.ccbcmd.edu/science/microbiology/index_gos.html.

Last updated:October, 2018
Please send comments and inquiries to Dr. Gary Kaiser

Fig. 7: E. coli Using a Type 3 Secretion System to Induce Pedestal Formation in a Host Cell

Fig. 7: E. coli Using a Type 3 Secretion System to
Induce Pedestal Formation in a Host Cell