Objectives for Bacterial Pathogenesis: Factors that Damage the Host

Learning Objectives for "Bacterial Pathogenesis: Factors that Damage the Host"
2. Producing Harmful Exotoxins
c. Type III Toxins that Interfere with Host Cell Function

After completing this section you should be able to perform the following objectives.

1.* Define A-B toxins and state the functions of the A component and the B component.

2. State how the following exotoxins cause harm and name a bacterium producing each:

a. diphtheria exotoxin

g. botulism exotoxin

b. cholera exotoxin

h. tetanus exotoxin

c. enterotoxins

i. Helicobacter toxins

d. pertussis exotoxin

j. Pseudomonas exotoxin A

e. shiga toxin

f. anthrax lethal toxin and edema toxin

Highlighted Bacterium

1. Read the description of Corynebacterium diphtheriae and match the bacterium with the description of the organism and the infection it causes.

2. Read the description of Bacillus anthracis and match the bacterium with the description of the organism and the infection it causes.

Think-Pair-Share Questions

Tetanus and diphtheria are very rare in the US because we immunize our population with the DTaP vaccine. Components of the vaccine include tetanus toxoid and diphtheria toxoid.

Explain the adaptive immune mechanism by which this immunization confers protection.

(*) or (**) = possible discussion question

RETURN TO "BACTERIAL PATHOGENESIS: FACTORS THAT DAMAGE THE HOST - PRODUCING HARMFUL EXOTOXINS: TYPE III TOXINS THAT INTERFERE WITH HOST CELL FUNCTIONS"

a. diphtheria exotoxin	g. botulism exotoxin
b. cholera exotoxin	h. tetanus exotoxin
c. enterotoxins	i. Helicobacter toxins
d. pertussis exotoxin	j. Pseudomonas exotoxin A
e. shiga toxin
f. anthrax lethal toxin and edema toxin