Fig. 5: ADP- Ribosylation of a Target Host Protein by an A-B Toxin

The A component of most A-B toxins catalyzes ADP-ribosylation of host cell target proteins. The ADP-ribosyl group is removed from the coenzyme NAD (see dashed line) and is covalently attached to a host cell target protein. This causes the inactivation of that target protein.

Illustration of ADP- Ribosylation of a Target Host Protein by an A-B Toxin .jpg by Gary E. Kaiser, Ph.D.
Professor of Microbiology, The Community College of Baltimore County, Catonsville Campus
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at https://cwoer.ccbcmd.edu/science/microbiology/index_gos.html.

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Last updated: August, 2019
Please send comments and inquiries to Dr. Gary Kaiser