Self Quiz for "Bacterial Pathogenesis: Factors that Damage the Host"
a. The Ability of PAMPs to Trigger the Production of Inflammatory Cytokines that Result in an Excessive Inflammatory Response: Gram-Negative PAMPsStudy the material in this section and then write out the answers to these questions.
Do not just click on the answers and write them out. This will not test your understanding of this tutorial.
1. State what is meant by endotoxin and where it is normally found. (ans)
2. Define healthcare-associated infection and name 3 common Gram-negative bacteria that cause HAIs. (ans)
3. We just learned that during a severe Gram-negative infection, LPS from the gram-negative cell wall can bind to macrophages causing their release of chemokines and cytokines and this is what then may lead to the often lethal shock cascade. Why would the human body evolve a mechanism for LPS binding to macrophages if it is potentially harmful? (ans)
Gary E. Kaiser, Ph.D.
Professor of Microbiology
The Community College of Baltimore County, Catonsville Campus
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work The Grapes of Staph at https://cwoer.ccbcmd.edu/science/microbiology/index_gos.html.
Last updated: August, 2019
Please send comments and inquiries to Dr.
Gary Kaiser