Self Quiz for "Bacterial Pathogenesis: Factors that Damage the Host"
a. Producing Cell Wall Components (PAMPs) that Bind to Host Cells causing them to Synthesize and Secrete Inflammatory Cytokine and Chemokiness: Gram-Negative Cell Wall Components

Study the material in this section and then write out the answers to these questions.
Do not just click on the answers and write them out. This will not test your understanding of this tutorial.

1. State what is meant by endotoxin and where it is normally found. (ans)

2. Briefly describe the steps behind the potentially fatal excessive inflammatory response that can occur during gram-negative septicemia. Use and describe the following key words in your description: (ans)

3. Define nosocomial infection and name 3 common gram-negative bacteria that cause nosocomial infections. (ans)

4. A culture of a patient with symptoms of meningitis shows a gram-negative diplococcus that is most likely Neisseria meningitidis. Among his symptoms are fever, a rash over the trunk, and signs of shock. In terms of the organism's structures, discuss what accounts for these symptoms. (ans)

5. We just learned that during a severe gram-negative infection, LPS from the gram-negative cell wall can bind to macrophages causing their release of chemokines and cytokines and this is what then may lead to the often lethal shock cascade. Why would the human body evolve a mechanism for LPS binding to macrophages if it is potentially harmful? (ans)

6. Multiple Choice (ans)

• RETURN TO "BACTERIAL PATHOGENESIS: FACTORS THAT DAMAGE THE HOST - PRODUCE CELL WALL COMPONENTS THAT BIND TO HOST CELLS CAUSING THEM TO SYNTHESIZE AND SECRETE INFLAMMATORY CYTOKINES AND CHEMOKINES: GRAM-NEGATIVE CELL WALL COMPONENTS"

• RETURN TO UNIT 2 TABLE OF CONTENTS

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