Self Quiz for Bacterial Pathogenesis: Factors that Damage the Host - Triggering the Secretion of Inflammatory Cytokines

Self Quiz for "Bacterial Pathogenesis: Factors that Damage the Host"
a. Producing Cell Wall Components (PAMPs) that Bind to Host Cells causing them to Synthesize and Secrete Inflammatory Cytokines and Chemokines

Study the material in this section and then write out the answers to these questions.
Do not just click on the answers and write them out. This will not test your understanding of this tutorial.

1. Matching:

_____ Intercellular regulatory proteins produced by one cell that subsequently bind to other cells in the area and influence their activity in some manner. Regulate body defense mechanisms. (ans)

_____ Defense regulatory chemicals that promote an inflammatory response by enabling white blood cells to leave the blood vessels and enter the surrounding tissue, by chemotactically attracting these white blood cells to the infection site, and by triggering neutrophils to release killing agents for extracellular killing. (ans)

_____ A condition where bacteria enter the bloodstream causing harm. (ans)

_____ A decreased volume of circulating blood. (ans)

_____ Reduced delivery of nutrients and oxygen via the blood. This can lead to ischemia, a restriction in blood supply that results in damage or dysfunction of tissue. (ans)

_____ Respiratory failure from acute inflammation in the lungs, injury to capillaries in the alveoli of the lungs, and pulmonary edema. (ans)

_____ The formation of clots within the blood vessels throughout the body. (ans)

A. inflammation
B. septicemia
C. chemokines
D. cytokines
E. DIC
F. ARDS
G. septic shock
H. hypovolemia
I. hypotension
J. hypoperfusion

2. Briefly describe the mechanism behind the shock cascade that can occur during septicemia. Use the following key words: (ans)

bacterial cell wall PAMPs	capillary damage
PRRs	hypotension
macrophages	hypovolemia
inflammatory cytokines	DIC
vasodilation	ARDS
inflammation	hypoperfusion of oxygen & nutrients
coagulation pathway	acidosis
complement pathway	shock
neutrophils	MOSF

3. Multiple Choice (ans)

RETURN TO "BACTERIAL PATHOGENESIS: FACTORS THAT DAMAGE THE HOST - PRODUCE CELL WALL COMPONENTS THAT BIND TO HOST CELLS CAUSING THEM TO SYNTHESIZE AND SECRETE INFLAMMATORY CYTOKINES AND CHEMOKINES"

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