Learning
Objectives for "Bacterial Pathogenesis: Factors that Promote Colonization
of the Host
5. The Ability to Resist Innate Immune Defenses such as Phagocytosis and Complement
c. The Ability to Resist Phagocytic Destruction"
After completing this section you should be able to perform the following objectives.
1. State 5 different ways bacteria might be able to resist phagocytic destruction once engulfed.
Think-Pair-Share Questions
Some bacteria, such as pathogenic Mycobacterium and Legionella pneumophilia prevent the acidification of the phagosome within phagocytes.
Why might this protect these bacteria from being killed within the phagocyte?
2. Staphylococcus aureus and Streptococcus pyogenes both produce a toxin called leukocydin.
How might this enable these bacteria to resist phagocytosis?
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Gary E. Kaiser
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Updated: Nov., 2011
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