Pathogen-Associated Molecular
Patterns Binding to Endocytic Pattern-Recognition Receptors on Phagocytes
Glycoprotein molecules known
as endocytic pattern-recognition receptors are found on the surface of phagocytes.
They are so named because they recognize and bind to pathogen-associated
molecular patterns - molecular components associated with microorganisms
but not found as a part of eukaryotic cells. These include bacterial
molecules such as peptidoglycan, lipoteichoic acids, mannans, and lipopolysaccharide
(LPS). These receptors enable the phagocyte to attach to the cell wall of
the microorganism so it can be engulfed and destroyed by lysosomes.
Flash animation illustrating Pathogen-Associated Molecular
Patterns Binding to Endocytic Pattern-Recognition Receptors on Phagocytes.swf by Gary E. Kaiser, Ph.D.
Professor of Microbiology,
The Community College of Baltimore County, Catonsville Campus
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at http://faculty.ccbcmd.edu/~gkaiser/index.html.
Last updated: August, 2018
Please send comments and inquiries to Dr.
Gary Kaiser
