Binding and Entry of an A-B Toxin
A-B toxins consist
of two parts, an A (active) component and a B (binding) component.
The B component of the exotoxin
binds to a receptor on the surface of a susceptible host cell. The
exotoxin now enters the host cell, in this case by endocytosis, and causes
harm by inactivating a host cell target protein through ADP-ribosylation.
GIF Animation of Binding and Entry of an A-B Toxin .gif by Gary E. Kaiser, Ph.D.
Professor of Microbiology,
The Community College of Baltimore County, Catonsville Campus
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at https://cwoer.ccbcmd.edu/science/microbiology/index_gos.html.
Last updated: August, 2019
Please send comments and inquiries to Dr.
Gary Kaiser