Self Quiz for Bacterial Pathogenesis: Factors that Damage the Host - Producing Exotoxins: Toxins that Damage Host Cell Membranes

Self Quiz for "Bacterial Pathogenesis: Factors that Damage the Host"
2. Producing Harmful Exotoxins
b. Type II Toxins: Exotoxins that Damage Host Cell Membranes

Study the material in this section and then write out the answers to these questions.
Do not just click on the answers and write them out. This will not test your understanding of this tutorial.

1. Match the following descriptions with the exotoxin:

_____ Damages cellular phospholipids causing tissue damage; stimulates inflammation. Produced by Pseudomonas aeruginosa. (ans)

_____ Causes lysis of white blood cells by damaging the cell membrane of phagocytes and possibly its lysosomes. It is produced by various pyogenic bacteria including Staphylococcus aureus and Streptococcus pyogenes. (ans)

_____ Produced by Streptococcus pneumonia, this toxin binds to cholesterol and puts pores in host cell membranes. It damages ciliated epithelial cells, lung tissue, and vascular endothelial cells. (ans)

_____ Produced by Streptococcus pyogenes, these hydrolytic enzymes destroy red blood cell membranes, cellular proteins, DNA, and fibrin respectively. The tissue damage due to these enzymes causes inflammation. (ans)

______ Causes the respiratory damage and violent coughing episodes seen during whooping cough. (ans)

a. leukocidin

b.phospholipase C

c. elastase

d. pneumolysin

e. streptoolysins, proteases, DNases, and streptokinase
f. Bordetella tracheal cytotoxin

2. Usually deep puncture-type wounds are needed for the development of gas gangrene. The resulting infected tissue shows massive edema, is mushy to the touch, and the infection spreads very rapidly through the tissue. In terms of the causative organism and its products, discuss why. (ans)

3. Multiple Choice (ans)

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