Self Quiz for The Life Cycle of SARS-CoV-2
Study the material in this section and then write out the answers to these questions.
Do not just click on the answers and write them out. This will not test your understanding of this tutorial.
1. Match the following:
_____ Appears to be the central organizer for coronavirus assembly. (ans)
_____ Responsible for virus binding to ACE-2 enzyme during viral adsorption. (ans)
_____ The structural component of the coronavirus localizing in the endoplasmic reticulum-Golgi region that structurally is bound to RNA genome of the virus. (ans)
a. S-protein
b. N-protein
c. E-protein
d. M-protein
2. Highly expressed in cells of the respiratory tract, such as type II alveolar cells (AT2) of the lungs, as well as cells such as enterocytes from the ileum and colon, kidney proximal tubule cells, bladder urothelial cells, and myocardial cells. The receptor for adsorption of SARS-CoV-2. (ans)
a. M-protein
b. S-protein
c. ACE-2 enzyme
d. E-protein
3. The genome of SARS-CoV-2 is _________________. (ans)
a. (-) single-stranded RNA ;
b. (+) single-stranded RNA
c. double-stranded DNA
d. (+) single-stranded DNA ;
d. double-stranded RNA ;
4. SARS-CoV-2 obtains its envelope from ________________________. (ans)
a. ERGICs ;
b. the host cell plasma membrane
c. the host cell nuclear membrane
5. What is the function of the various short subgenomic mRNAs in SARS-CoV-2? (ans)
a. Function as the (+) single stranded genome of the virus ;
b. Codes for viral proteins such as the S, M, E, N proteins, and non-structural proteins of the virus.
c. Codes for the production of inflammatory cytokines by the virus.
6. How is SARS-CoV-2 released from the host cell? (ans)
a. By budding from the host cell plasma membrane. ;
b. By endocytosis.
c. By host cell lysis.
d. By exocytosis.
Last updated: Feb., 2020
Please send comments and inquiries to Dr.
Gary Kaiser