Think-Pair-Share Questions

1. State the role(s) of gp120 and gp41 in the life cycle of HIV.

2.Why does HIV primarily infect T4-lymphocytes, macrophages, and dendritic cells?

3. How do antiretroviral drugs that bind to HIV-encoded protease help to reduce the number of HIV in the body.

4. If one could destroy all of the infected white blood cells in a person infected with HIV and then reconstitute the cells by giving a bone marrow transplant from a person homozygous for a deletion mutation in their gene coding for the chemokine receptor CCR5 (he or she can not make CCR5 molecules), describe how this might prevent HIV infection in the person receiving the transplant.