To replicate the viral genome, DNA-dependent DNA polymerase enzymes copy both the (+) and (-) DNA strands producing dsDNA viral genomes.
To produce viral mRNA molecules. DNA-dependent RNA polymerase enzymes copy the (-) DNA strand into (+) viral mRNA. The (+) viral mRNA can then be transtated into viral proteins by host cell ribosomes.
Last updated: Feb., 2018
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Gary Kaiser