Fig. 6: Action of Maraviroc in Blocking CCR5

M-tropic strains of HIV bind to first to a CD4 molecule and then to a chemokine co-receptor called CCR5. This binding to dual receptors is necessary for the virus to enter the host cell. The drug maraviroc (Selzentry) blocks the CCR5 co-receptor on host cells so that HIV cannot adsorb to the cell.

Illustration of Action of Maraviroc in Blocking CCR5. .jpg by Gary E. Kaiser, Ph.D.
Professor of Microbiology, The Community College of Baltimore County, Catonsville Campus
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at http://faculty.ccbcmd.edu/~gkaiser/index.html.

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Last updated: August, 2019
Please send comments and inquiries to Dr. Gary Kaiser